DPAG HoD Seminar: 'New Discoveries in Heart: Vascular Signaling and Heart Function'
Audience: Member of University - ALL Format: In Person
Friday, 22 May 2026, 1pm to 2pm
Recent work in my lab (and a few others) has provoked critical new questions about how heart, brain and kidney - the "heavy lifters" of our biology - work! While the answers to critical questions are elusive and the experiments are exceedingly difficult, provocative findings will be shown and discussed. During this presentation, I will focus on the heart. In many ways, it is the simplest of these three organs. Despite that simplicity, there is a good chance that our answers will be a bit wrong. The primary controlling signal is electrical, and it arises because of metabolic changes in ventricular myocytes. My colleagues and I hypothesize that such "electro-metabolic signaling" (EMS) significantly contributes to blood flow regulation in heart. Through EMS, the metabolic activity of the heart muscle itself regulates the required blood flow.
Speaker(s): Professor Jonathan Lederer (University of Maryland School of Medicine)
Series: DPAG Head of Department Seminar Series
Venue:
Sherrington Building - Sherrington Library
-
Sherrington Library Sherrington Building off Parks Road Oxford Oxfordshire OX1 3PT United Kingdom
Department: Physiology Anatomy and Genetics (Department)
Host: Dr Liron Boyman