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SUMMARY:Scalable Tools to Map T Cell Recognition
DTSTART;TZID=Europe/London:20260601T150000
DTEND;TZID=Europe/London:20260601T160000
DTSTAMP:20260517T123459Z
UID:12119946-6850-f111-bec7-6045bdcfe41f
CREATED:20260515T141345Z
DESCRIPTION:Part of the webinar series Unravelling T Cell Recognition: Ins
 ights from Immunology and AI.\n\nT cells recognise specific antigens in ca
 ncer\, infection\, and autoimmunity through highly diverse T cell receptor
 s (TCRs)\, yet systematically mapping TCR specificity at scale remains a m
 ajor challenge in immunology.\n\nIn this webinar\, Dr Stephanie Gaglione (
 Gladstone Institutes) will present new scalable experimental and functiona
 l screening platforms designed to decode antigen-specific T cell recogniti
 on. The talk will cover TCRAFT\, a modular approach for rapid large-scale 
 TCR reconstruction while preserving native chain pairing\, alongside RAPTR
  and VelociRAPTR technologies for high-throughput receptor–ligand screen
 ing across millions of TCR variants and peptide antigens.\n\nThese approac
 hes provide new opportunities to understand\, engineer\, and therapeutical
 ly manipulate antigen-specific immune responses across autoimmunity\, infe
 ction\, and cancer immunotherapy.\n\nHosted by Prof Hashem Koohy\, Associa
 te Professor of Systems Immunology\, University of Oxford.
LAST-MODIFIED:20260515T142549Z
SPEAKER:Dr Stephanie Gaglione (Gladstone Institute)
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