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SUMMARY:Dr Thomas Vogl- Center for Cancer Research at the Medical Universi
 ty of Vienna
DTSTART;TZID=Europe/London:20260605T130000
DTEND;TZID=Europe/London:20260605T140000
DTSTAMP:20260526T075204Z
UID:1d701d67-2642-f111-bec6-6045bdcfe41f
CREATED:20260427T104700Z
DESCRIPTION:Our current conception of antibody repertoires is mostly based
  on DNA sequencing of the corresponding BCR sequences\, whereas the actual
  antigens recognized are vastly unknown. My lab strives to unravel the fun
 ctional capacity of these enormous immune repertoires targeting microbiota
  and to shed light on their role in different diseases contexts such as au
 toimmune diseases and cancer. We are leveraging a high throughput phage di
 splay system to screen for hundreds of thousands of antigens in parallel (
 Vogl et al.\, 2021\, Nature Medicine).\nHere\, I will give an overview on 
 the technology\, recent applications to diseases\, as well as unpublished 
 work around the development of the immune system\, and immunogenetics. \n\
 nshort biography:\nThomas Vogl is an Austrian molecular biologist and immu
 nologist whose work focuses on understanding how the human immune system i
 nteracts with the gut microbiome and how this relationship influences dise
 ases. As a group leader at the Center for Cancer Research at the Medical U
 niversity of Vienna\, he combines experimental biology with computational 
 approaches such as machine learning and bioinformatics to study complex im
 mune responses. \nDr. Vogl’s scientific approach relies on high-throughp
 ut immunological techniques\, including advanced antibody-profiling techno
 logies and automated laboratory systems\, enabling large-scale analysis of
  immune responses from thousands of patient samples. His research has iden
 tified novel biomarkers and deepened understanding of how antibodies inter
 act with microbial structures\, which may contribute to cancer\, autoimmun
 e disorders\, and other diseases.\nEducated in molecular biomedical scienc
 es in Austria\, Dr. Vogl conducted postdoctoral research in Australia and 
 Israel\, where he expanded his expertise in data science and immunomics. H
 e has received major distinctions\, including an ERC Starting Grant and is
  coordinating the EU consortium ID-DarkMatter-NCD. Overall\, his research 
 advances personalized medicine by clarifying immune-microbiome interaction
 s and improving strategies for disease diagnosis and therapy.
LAST-MODIFIED:20260427T104709Z
LOCATION:Henry Wellcome Building Rooms A & B\, Room A+B Wellcome Trust Cen
 tre for Human Genetics Headington Oxford Oxfordshire OX3 7BN United Kingdo
 m
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