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SUMMARY:Barrier immune niches during microbial colonization and infection
DTSTART;TZID=Europe/London:20260624T140000
DTEND;TZID=Europe/London:20260624T150000
DTSTAMP:20260602T114735Z
UID:f03ca352-975d-f111-a825-7c1e52046a23
CREATED:20260601T085320Z
DESCRIPTION:Barrier tissues are portals to the microbial-dense world. Barr
 iers are defined by heterogeneous epithelial linings and deeper stromal ce
 lls. Here\, I will discuss two recent efforts from our group that focus on
  microbial-immune positioning and coordination at the skin and respiratory
  tract barriers. In the skin\, we compared colonization by the fungal path
 obionts Candida auris versus C. albicans to illuminate distinct fungal-imm
 une interactions. C. auris exhibited enhanced skin persistence and hair fo
 llicle tropism. In the lung\, we defined the spatiotemporal stromal-immune
  response to Influenza A virus infection\, focusing on the underappreciate
 d role of fibroblasts and their dynamic states.
LAST-MODIFIED:20260601T085619Z
LOCATION:Kennedy Institute of Rheumatology - Kennedy Lecture Theatre\, Ken
 nedy Lecture Theatre Kennedy Institute of Rheumatology Headington Oxford O
 xfordshire OX3 7FY United Kingdom
SPEAKER:Dr. Ari Molofsky (The University of California\, San Francisco)
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