Organ Crosstalk Immunology in the Exposome Era

Monday, 6 July 2026, 12pm to 1pm

In response to localised tissue exposures, spatially and temporally regulated signals can transit from the affected site to influence cells in distal target organs, mediating an organism-wide response. It is now clear that the immune system acts as both an initiator and a sensor of this organ-to-organ communication (organ crosstalk immunology), but we still have limited knowledge of the outcomes that such crosstalk confers. Contrasting peripheral immune features following mucosal infection with those that associate with brain injury (ischaemic stroke), this talk will explore how co-ordinated local and systemic immune cell instruction influences organismal morbidity and survival.

Speaker(s): Prof. John Grainger (The University of Manchester)

Series: Kennedy Institute of Rheumatology External Seminar Series

Venue: Kennedy Institute of Rheumatology - Kennedy Lecture Theatre - Kennedy Lecture Theatre Kennedy Institute of Rheumatology Headington Oxford Oxfordshire OX3 7FY United Kingdom

Department: Kennedy Institute of Rheumatology (Unit)

Organiser: Tess Lawless

Host: Prof Dame Fiona Powrie DBE FRS FMedSci